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Cancer Potency of Polycyclic Aromatic Hydrocarbons | TestAmerica Laboratories

Cancer Potency of Polycyclic Aromatic Hydrocarbons

Minnesota Department of Health Guidance

On February 8, 2016, Minnesota Department of Health (MDH) issued Guidance for Evaluating the Cancer Potency of Polycyclic Aromatic Hydrocarbons [PAH] Mixtures in Environmental Samples.  Within this document, there is one approach for assessing PAH cancer potency that relies on environmental analytical data for a list of carcinogenic PAHs (cPAH) from site samples.  The MDH Priority cPAH list is an extended list of PAHs as compared to the EPA’s Priority Pollutant or Target Compound lists.  Regulatory authority regarding the evaluation of cPAHs is the responsibility of the Minnesota Pollution Control Agency (MPCA).  Guidance is detailed in Interim Policy on Implementing MDH’s Revised cPAH Guidance.  [See What’s New - Carcinogenic polycyclic aromatic hydrocarbons (cPAH))

Benzo(a)pyrene (BaP) is the index compound (i.e. potency factor of 1).  Using the cPAH relative potency evaluation, each cPAH is presumed to contribute to the potency of a mixture in proportion to its concentration in the sample and its own potency.

TestAmerica's Analytical Approach

TestAmerica Nashville offers a test method for the full list of Minnesota Priority cPAH compounds applicable to projects that require site specific cPAH data.  Reporting limits listed below are general reference values, and do not take into account potential matrix issues which may impact and elevate the final reporting limits for your samples.  Please contact your Project Manager for additional details.

CASRN

MDH Priority cPAHs

Relative Potency Factors

Reporting Limit

(ug/kg)

Reporting Limit

(ug/l)

191-26-4

Anthanthrene

0.4

0.66

0.02

56-55-3

Benz[a]anthracene

0.2

0.66

0.02

50-32-8

Benzo[a]pyrene

1

0.66

0.02

205-99-2

Benzo[b]fluoranthene

0.8

0.66

0.02

205-12-9

Benzo[c]fluorene

20

0.66

0.02

‎191-24-2

Benzo[g,h,i]perylene

0.009

0.66

0.02

205-82-3

Benzo[j]fluoranthene

0.3

0.66

0.02

207-08-9

Benzo[k]fluoranthene

0.03

0.66

0.02

218-01-9

Chrysene

0.1

0.66

0.02

27208-37-3

Cyclopenta[c,d]pyrene

0.4

0.66

0.02

53-70-3

Dibenz[a,h]anthracene

10

0.66

0.02

192-65-4

Dibenzo[a,e]pyrene

0.4

0.66

0.02

189-64-0

Dibenzo[a,h]pyrene

0.9

0.66

0.02

189-55-9

Dibenzo[a,i]pyrene

0.6

0.66

0.02

191-30-0

Dibenzo[a,l]pyrene

30

0.66

0.02

206-44-0

Fluoranthene

0.08

0.66

0.02

193-39-5

Indeno[1,2,3-cd]pyrene

0.07

0.66

0.02

3697-24-3

5-Methylchrysene

1

0.66

0.02

7496-02-8

6-Nitrochrysene

10

0.66

0.02