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bioavailability testing, bioaccessibility testing

Bioavailability and Bioaccessibility

Bioavailable Testing Versus Bulk Testing

TestAmerica supports the analysis of a wide variety of tests to evaluate the bioavailability or the bioaccessibility of specific constituents of concern related to sediment sites.  In the laboratory context, bioavailability refers to the amount of a contaminant of concern that is available for uptake by an organism or matrix.  Historically, much of the evaluation of the potential effect of sediment contamination on human health and the environment has been based on bulk sediment analysis. Many years of research has demonstrated that the bioavailable concentrations of many constituents of concern may be less than the total concentration in the sediment.  Therefore, if the bioavailability of a constituent of concern is less than that of the bulk concentration, bioavailability considerations can be incorporated into a project.

How Can TestAmerica Help You With Bioavailability and Bioaccessibility Testing?

TestAmerica has a wide variety of tools and methods to evaluate the bioavailablity of specific constituents of concern related to sediment and the water column. Our support includes participating in setting project goals, selecting the best analytical approach for the constituents of concern, evaluating potential passive sampling media, and quality control requirements for the project.

TestAmerica’s Solutions to Bioavailability/Bioassessibility Challenges

The table below outlines TestAmerica's method offerings for bioavailability/bioassessibility testing:

TestAmerica's Approach

Analytical Method

Acid Volatile Sulfides / Simultaneously Extracted Metals (AVS/SEM)

Determination of Acid Volatile Sulfide and Selected Simultaneously Extracted Metals in Sediment, EPA-821-R-100

Black Carbon (BC) and Total Organic Carbon (TOC)

TestAmerica SOP and other references for Black Carbon; EPA Method 9060 or Lloyd Kahn Procedure for TOC

In Vitro Bioaccessibility Arsenic (IVBA) and Lead

TestAmerica SOP based on EPA’s SW-846 Method 1340 In Vitro Bioaccessibility for Lead in Soil and other references

Passive Samplers for organics including PAHs, Pesticides, PCBs, Dioxins/Furans using Polyethylene (PE), Polyoxymethylene (POM), Polydimethylsiloxane PDMS & Solid Phase Micro-Extraction (SPME) fibers

Project Specific Procedures

Passive Sampler  using DGT  for Mercury

Project Specific Procedures

Peepers support for organics, inorganics and classical wet chemistry

Project Specific Procedures

Pore Water Generation by centrifugation for organics, inorganics, and classical wet chemistry

TestAmerica SOP for Pore Water Generation and subsequent analysis

Seven Step Sequential Extraction Procedure (SEP) for up to 23 metals

TestAmerica SOP

Semi-Permeable Membrane Device (SPMD)

Project Specific Procedures