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Part 5 - TOP Assay: One Way to Look at Future Risk from Precursors

Event Announcement

Tuesday, Jun 30, 2020

About This Webinar:

Current analytical methodologies measure a discrete list of approximately 30 (PFAS) compounds. Many additional PFAS are not determined as discrete compounds by existing commercial methods. Hence, we may be underestimating the PFAS mass present in the environment. There is significant pressure from the public, environmental agencies, and others to apply methodologies that more closely measure the full extent of PFAS contamination.

Eurofins implemented the TOP assay as a solution to this problem. The TOP assay rapidly converts PFAA (perfluoroalkyl acids) precursors into PFAAs including PFOA, replicating what micro-organisms in the environment would achieve over time. This quantifies the sum of PFAS that could be converted to PFAAs in the environment. TOP assays have revealed that for AFFF-impacted sites, existing analytical methods only detect an estimated 30% to 50% of the total PFAA mass present as PFAA precursors.

In 2006, the United States Environmental Protection Agency (US EPA) announced the PFOA Stewardship Program, to phase out the emissions and the use of long-chain perfluorinated chemicals (PFCs), by December 31st, 2015. In addition, the US EPA and State agencies have developed health advisories or screening levels for a number of PFAAs, as these chemicals are persistent, bioaccumulative, and toxic.

Topics the Presentation Will Cover Include:

  • What is the TOP Assay
  • How does it work?
  • TOP Assay chemical reaction
  • What do the results mean?
  • What are the limitations of the assay?
  • Future concerns
  • Capabilities and questions

A question and answer session will immediately follow the presentation.

June 30, 2020 - 1:30 P.M. ET